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Up to the late 1950s, few infants born with spina bifida aperta were treated actively and there was a wish, usually realised, that they would die.
Neural tube defects - ie, craniorachisisis, anencephaly, and spina bifida aperta - are amongst the commonest congenital abnormalities.
As a result, thinning of the uterine wall or dehisscence which have been among the most worriesome and critizised complications after the open operative approach do not occur following minimally-invasive fetoscopic closure of spina bifida aperta.