spherocytosis

Measuring iron stores is therefore considered part of the diagnostic approach to hereditary spherocytosis.

The term "non hereditary spherocytosis" is occasionally used, albeit rarely.

The primary defect in hereditary spherocytosis is a deficiency of membrane surface area.

At this point, there exists no cure for the genetic defect that causes hereditary spherocytosis.

It almost always refers to hereditary spherocytosis.

As in non-hereditary spherocytosis, the spleen destroys the abnormal spherocytes.

Spherocytes are found in hereditary spherocytosis and autoimmune hemolytic anemia.

It has turned out that Daubert suffered from a hereditary blood disorder called hemolytic spherocytosis, which contributed to his death.

Mutations in erythrocytic ankyrin 1 have been associated in approximately half of all patients with hereditary spherocytosis.

Individuals with reduced or defective ankyrinR have a form of hemolytic anemia termed hereditary spherocytosis.

Chauffard is remembered for his work involving liver disease and his pathophysiological research of hereditary spherocytosis.

Characteristic red blood cell abnormalities are anemia, sickle cell anemia and spherocytosis.

In hereditary spherocytosis, erythrocytes fail to pass through and get phagocytosed, causing extravascular hemolysis.

Defects of red blood cell membrane production (as in hereditary spherocytosis and hereditary elliptocytosis)

Although the osmotic fragility test is widely considered the gold standard for diagnosing hereditary spherocytosis, it misses as many as 25% of cases.

"Minkowski-Chauffard disease": Congenital hemolytic anemia with spherocytosis, splenomegaly and jaundice.

As in spherocytosis, the spleen's hemolysis results in observational symptoms of Fatigue (physical), pallor, and jaundice.

In people with sickle-cell disease or other forms of chronic hemolytic anemia such as hereditary spherocytosis, infection can precipitate an aplastic crisis.

Castle and his team later characterized the red blood cell defects that are responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis.

Mutations of spectrin and protein 4.1 are associated with elliptocytosis or spherocytosis and anemia of varying severity.

Check the slide for spherocytosis (e.g. in hereditary spherocytosis, among other causes)

To decrease the risk of sepsis, post-splenectomy spherocytosis patients require immunization against the pneumococcus bacterium, influenza virus, and prophylactic antibiotic treatment.

These changes are also seen in non-hereditary spherocytosis, but they are typically more marked in hereditary spherocytosis.

If infection occurs in individuals with sickle cell anemia or spherocytosis, that will lead to incorporation of 2 anemia-induced mechanisms: decrease red cell production and hemolysis.

Risk factors for pigment stones include hemolytic anemias (such as sickle-cell disease and hereditary spherocytosis), cirrhosis, and biliary tract infections.