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Bilateral spastic paresis may develop and pressure, vibration and touch sense are diminished.
Neuropsychiatric manifestations of pellagra include headache, irritability, poor concentration, anxiety, hallucinations, stupor, apathy, psychomotor unrest, photophobia, tremor, ataxia, spastic paresis, fatigue, and depression.
After stroke or spinal cord injury in humans, spastic hypertonus (spastic paresis or spastic paralysis) often develops, whereby the stretch reflex in flexor muscles of the arms and extensor muscles of the legs is overly sensitive.