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It is also capable of causing a paralytic disorder, tropical spastic paraparesis.
The virus has also been linked to a rare serious paralytic disease, tropical spastic paraparesis.
They cause two life-threatening diseases, adult T cell leukaemia/lymphoma and tropical spastic paraparesis.
Familial spastic paraparesis, a hereditary disorder.
KIF1A is associated with hereditary spastic paraparesis.
Infection by human T-lymphotropic virus can lead to tropical spastic paraparesis and adult T-cell leukemia.
After the initial weeks of functional improvement, the spastic paraparesis remains stable for the rest of life, as confirmed by longterm follow-up studies.
Some patients may suffer an abrupt aggravating episode, e.g. a sudden and permanent worsening of the spastic paraparesis.
It has also been linked strongly to a neurological disease, tropical spastic paraparesis, found in Africa, the Caribbean and southern Japan.
More proximal portions of the medial striate artery may cause spastic paraparesis and sensory loss contralateral to the lesioned side.
The medical terminology began to fly - "spastic paraparesis," "hyper-reflexia," "kappa light chain protein" found in his urine specimens.
For several decades, the term tropical spastic paraparesis was used to describe a chronic and progressive clinical syndrome that affected adults living in equatorial areas of the world.
Abdallat-Davis-Farrage syndrome is a phakomatosis consisting of disordered skin and hair pigmentation, progressive spastic paraparesis and peripheral neuropathy.
The onset of paralysis (spastic paraparesis) is sudden and symmetrical, affecting the legs more than the arms and the resulting disability is permanent, but does not progress.
Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia as well as fatty acid hydroxylase-associated neurodegeneration.
Progressive spastic paraparesis, vitiligo, premature graying, and distinct facial appearance: A new genetic syndrome in 3 sibs (1981), American Journal of Medical Genetics (9:4)
A missense mutation (K382N) in VPS37A protein has been shown to cause complex hereditary spastic paraparesis (cHSP).
Forms of complicated spastic paraparesis and pure spastic paraparesis (designated SPG2) are also caused by the PLP1 gene.
Only 0.25-2% of the infected individuals will develop a progressive neurologic disease named HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP).
Threonine is used to treat various nervous system disorders including spinal spasticity, multiple sclerosis, familial spastic paraparesis, and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease).
HTLV-II has not been clearly linked to any disease, but has been associated with several cases of myelopathy/tropical spastic paraparesis (HAM/TSP)- like neurological disease.
The severity of konzo varies from hyperreflexia in the lower limbs to a severely disabled, bedridden patient with spastic paraparesis, associated weakness of the trunk and arms, impaired eye movements, dysarthria and possibly visual impairment.
Since then, this condition has been named HTLV-1-associated myelopathy/tropical spastic paraparesis or HAM/TSP, and scientists now understand that it is a condition caused by a virus that results in immune dysfunction.
Tropical spastic paraparesis (TSP), also known as HTLV-associated myelopathy or chronic progressive myelopathy, is an infection of the spinal cord by Human T-lymphotropic virus resulting in paraparesis, weakness of the legs.
In complicated cases of autosomal dominant optic atrophy, in addition to bilateral optic neuropathy, several other neurological signs of neurological involvement can be observed: peripheral neuropathy, deafness, cerebellar ataxia, spastic paraparesis, myopathy.