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"A small interfering RNA is a neat molecular way of being able to turn off one gene within cells," he said.
Transfection consists in introducing a gene or a small interfering RNA into cells.
The pieces are known as small interfering RNA's or siRNA's.
The inactivation of Twist by small interfering RNA or chemotherapeutic approach has been demonstrated in vitro.
Exosomes can be considered a promising carrier for effective delivery of small interfering RNA due to their existence in body's endogenous system and high tolerance.
Other technologies employ antisense, small interfering RNA and other DNA.
These classifiers would use a small interfering RNA which targeted the repressor and activator in the Lac operon.
There has been an observed similarity between the suppression of the transposable element TY1 in yeast and small interfering RNA activity within plants.
Small interfering RNA (siRNA) prevents the production of specific proteins by blocking the genes which code for them.
Small interfering RNA (siRNA)
Atu027 is a small interfering RNA (siRNA) molecule that is being developed for the treatment of solid tumours.
Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis.
It did not take scientists long to realize that micro-RNA and small interfering RNA's were the same length and used much of the same mechanism.
They also found that targeting MEK1 and Cyclin E1 with small interfering RNA decreased the number of endothelial cells.
Repeat associated small interfering RNA (rasiRNAs) are considered to be a subspecies of piRNA.
Removal of endogenous LYK5 by small interfering RNA abrogates LKB1-induced G1 phase arrest.
Sirna's development pipeline includes several small interfering RNA (siRNA) drugs, thought to stably silence the expression of specific disease-related genes.
"It comes down to whether you can deliver the small interfering RNA to the cells where it is needed and get it inside the cells," said Dr.
With Andrew Hamilton he discovered the small interfering RNA that is the specificity determinant in RNA-mediated gene silencing.
Small interfering RNA (siRNA) is a class of double-stranded RNA molecules, 20-25 base pairs long.
Small interfering RNA (siRNA) surrounds a gold nanoparticle like a shell; the nucleic acids are highly oriented, densely packed and form a tiny sphere.
Small interfering RNA (siRNA) can induce a selective degradation of the mRNA of the protein of interest.
RNA polymerase IV is an enzyme which synthesizes small interfering RNA (siRNA) in plants.
This technique makes it possible to cross the cellular barriers and deliver a gene or a small interfering RNA (siRNA) into the cells for research or therapeutic purposes.
If an mRNA molecule has a complementary sequence to a small interfering RNA then it is targeted for destruction via the RNA interference pathway.