similar fold

Scores between 70 and 80 indicate a similar fold with minor variations.

Similar fold and thrust model of origin is known from the other areas of alpine system.

The structure of 7 out of the 15 domains has been determined, using X-ray crystallography, and they seem to share a similar fold.

Many protein domains have less than 10% sequence identity, and yet possess a similar fold and possibly related function.

To the south-west across the Test is a similar fold, the Dean Hill Anticline.

Similar fold patterns are present in the northern Park Range and Medicine Bow Mountains.

A similar fold structure continues east from here, but offset en echelon to the south as the Littlehampton Anticline.

The hexon coat protein is a duplication consisting of two domains with a similar fold packed together like the nucleoplasmin subunits.

Folding under this mechanism is typically of the similar fold style, as thinned limbs are shortened horizontally and thickened hinges do so vertically.

Both mevalonate kinase and mevalonate diphosphate decarboxylase probably evolved from a common ancestor since they have a similar fold and catalyze phosphorylation of similar substrates.

The first structure of a GAF domain solved by Ho and colleagues showed that this domain shared a similar fold with the PAS domain.

AUH has a similar fold that is found in other members of the enoyl-CoA hydratase/isomerase family; however, it is a hexamer as a dimer of trimers.

The crystal structure, resolved at 2.4A resolution, reveals that AR1 has a very similar fold to AR2, both repeats being jelly-roll motifs, composed of four-stranded and five-stranded antiparallel beta-sheets.

Phase III query, due for release later in the year, will extend these Phase II features and include the ability to query non-redundant sets of data based upon both sequence and similar fold.

Although the reason behind the lower activation potential is unknown, at least in PfPP5 it correlates with a similar fold activation following loss of the TPR domains through either mutagenesis or proteolytic cleavage (Fig.

Weak sequence similarity and pronounced secondary structure similarity between GGDEF domains and the catalytic domains of adenylate cyclases (AC) have led to the hypothesis that DGCs and ACs share a similar fold.

There is, therefore, a good chance (currently 70-80%) that a protein which has a similar fold to the target protein has already been studied by X-ray crystallography or nuclear magnetic resonance (NMR) spectroscopy and can be found in the PDB.

The first part describes the use of MAMA for creating and improving masks; the second part outlines the use of DEJAVU when only a rough skeleton is available to look for proteins with similar fold in the PDB.

Consequently, the roughly folded structure of a protein (its "topology") is conserved longer than its amino-acid sequence and much longer than the corresponding DNA sequence; in other words, two proteins may share a similar fold even if their evolutionary relationship is so distant that it cannot be discerned reliably.