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A significant number of signet ring cells, generally, are associated with a worse prognosis.
The signet ring cell carcinoma form carries a worse prognosis.
The name of the cell comes from its appearance; signet ring cells resemble signet rings.
Signet ring cell definition - cancer.
Signet ring cell cancer information - sites.google.com/site/signetringcancer.
Signet ring cells - med.Utah.edu.
In histology, a signet ring cell is a malignant cell type seen predominantly in carcinomas.
Signet ring cells resemble signet rings because a large vacuole full of mucin displaces the nucleus to the periphery.
For example, neoplasms characterized by high-grade features, invasive glands and or signet ring cells, are termed adenocarcinoma in pathology literature (e.g., [2].
Signet ring cell squamous cell carcinoma (occasionally rendered as "signet-ring-cell squamous-cell carcinoma") is a histological variant of skin cancer.
Signet ring cell carcinoma is an epithelial malignancy characterized by the histologic appearance of signet ring cells.
Some studies suggest that the papillary adenocarcinoma and the signet ring cell adenocarcinoma variants are more likely to carry this fused gene than other histological variants.
In May, 2013, OHS math teacher Alla Bogomolnaya passed away due to a rare and very aggressive form of colon cancer called signet ring cell adenocarcinoma.
Signet ring cells are most frequently associated with stomach cancer, but can arise from any number of tissues including the prostate, bladder, gallbladder, breast, colon, ovarian stroma and testis.
The pool of mucin in a signet ring cell mimics the appearance of a finger hole and the nucleus mimics the appearance of the face of the ring in profile.
Other exocrine cancers include adenosquamous carcinomas, signet ring cell carcinomas, hepatoid carcinomas, colloid carcinomas, undifferentiated carcinomas, and undifferentiated carcinomas with osteoclast-like giant cells.