sickling

The sickling occurs because of a mutation in the hemoglobin gene.

The leading causes of death in youth sports are sudden cardiac arrest, concussion, heat illness and external sickling.

Mutant beta globin is responsible for the sickling of red blood cells seen in sickle cell anemia.

Fadulu's research used an extract of the African "chewing stick," which he discovered, reverses sickling of red blood cells.

Since the sickling of parasite infected cells is higher, these selectively get removed by the reticulo-endothelial system, thus sparing the normal erythrocytes.

For example, students are taught to avoid sickling of the foot, which is an undesirable aesthetic and can result in ankle injuries when performing en pointe.

This causes sickling of that particular erythrocyte, signalling the phagocytes to get rid of the cell and hence the parasite within.

In an aqueous solution, it has prevented irreversibly the in vitro sickling of hemoglobins containing human erythrocytes during deoxygenization.

In 1927 Vernon Hahn and Elizabeth Biermann Gillespie showed that sickling of the red cells was related to low oxygen.

So far, the calcium blockers verapamil, diltiazem and nifedipine have been shown to relieve some sickling or sickling-related complications, while nitrendipine did not work as well.

Sickle cell nephropathy is a type of nephropathy associated with sickle cell disease, it causes renal complications as a result of sickling of red blood cells in the microvasculature.

Some types of injuries are prevented by adhering to proper technique such as correct upper-body positioning, maintaining straight knees when required, keeping body weight centered over the box of the shoes, and avoiding sickling.

The hypertonic and relatively hypoxic environment of the renal medulla, coupled with the slow blood flow in the vasa recta, favors sickling of red blood cells, with resultant local infarction (papillary necrosis).

Those with only one of the two alleles of the sickle-cell disease are more resistant to malaria, since the infestation of the malaria plasmodium is halted by the sickling of the cells which it infests.

In June 2007 the National Athletic Trainers' Association released a consensus statement noting that approximately 5 percent of exertional deaths in young healthy athletes were from exertional sickling in those with sickle cell trait.

Additionally, clotrimazole is used to treat the sickling of cells (related to sickle cell anemia) by blocking ion channels or clocip B channels in the red blood cell membrane, keeping ions and water within the cell.

Dr. Dean Sickling also received the National Science and Technology Medal from President George W. Bush, in part due to his work on the SAFER Barrier and on other roadside safety devices.