serine-threonine kinase

Researchers were able to demonstrate that these genes encode enzymes that have serine-threonine kinase activity.

In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1.

The WNK4 gene encodes a serine-threonine kinase expressed in distal nephron.

This gene encodes a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins.

Serine-threonine kinase receptor-associated protein is an enzyme that in humans is encoded by the STRAP gene.

The 160 kD protein product was first discovered in a screen for novel substrates of the serine-threonine kinase Akt, which phosphorylates AS160 after insulin stimulation.

Another protein essential for the SI response is MLPK, a serine-threonine kinase, which is anchored to the plasma membrane from its intracellular side.

The protein is a serine-threonine kinase that is activated by another protein called either Dbf4 in the yeast Saccharomyces cerevisiae or ASK in mammals.

Glycogen synthase kinase-3 (GSK-3) is a proline-directed serine-threonine kinase that was initially identified as a phosphorylating and an inactivating agent of glycogen synthase.

TRAF2 in turn recruits the multicomponent protein kinase IKK, enabling the serine-threonine kinase RIP to activate it.

Myotonin-protein kinase is a serine-threonine kinase that is closely related to other kinases that interact with members of the Rho family of small GTPases.

The serine-threonine kinase Mst1, a member of a family of kinases homologous to the Ste20 kinase in yeast, has recently been identified as a RAPL effector.

NODs transduce signals in the pathway of NF-κB and MAP kinases via the serine-threonine kinase called RIP2.

BMPR1A is a serine-threonine kinase type I receptor of the TGF-beta superfamily that, when activated, leads to phosphorylation of SMAD4.

The Cdc7/Dbf4 kinase complex, along with another serine-threonine kinase, cyclin-dependent kinase (Cdk), phosphorylates the pre-RC which activates it at the G1/S transition.

BMP4, as a member of the transforming growth factor-β (TGF-β) family binds to a 2 different types of serine-threonine kinase receptors known as BMPR1 and BMPR2.

Like other members of the TGF-β superfamily, BMPs induce intracellular signaling via heteromeric complexes of the type I and type II serine-threonine kinase receptors [ 5 6 ] .

Type I T. gondii rhoptry effector molecule Rop18, a serine-threonine kinase, was recently shown to selectively phosphorylate and inactivate the "pioneer" IRGs, thereby preventing their assembly, activation and destruction of the T. gondii vacuole within monocytes.

Examples and other names in common use include Cdc5, Cdc5p, Plk, PLK, Plk1, Plo1, POLO kinase, polo serine-threonine kinase, polo-like kinase, polo-like kinase 1, serine/threonine-specific Drosophila kinase polo, and STK21.