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IgM is primarily found in serum; however, because of the J chain, it is also important as a secretory immunoglobulin.
Antibacterial compounds (thiocyanate, hydrogen peroxide, and secretory immunoglobulin A)
Secretory immunoglobulin A levels were increased, while levels of IL-15 and IL-6 were decreased.
"Pelargonium sidoides extract modulates the production of secretory immunoglobulin A in saliva, both interleukin-15 and interleukin-6 in serum, and interleukin-15 in the nasal mucosa.
Moreover, commensals are known to induce Th1 response and anti-inflammatory interleukin (IL)-10, antimicrobial peptides, FOXP3, secretory immunoglobulin A (sIgA) production.
Intestinal bacteria are also shown to improve the secretory immune function and the intestinal flora such as influencing secretory immunoglobulin A (sIgA) synthesis and sIgA precursors.
The saliva from the stranger, granted that he or she is healthy and consistent with his or her oral hygiene, is relatively clean and contains enough antimicrobial compounds such as lactoferrin, lactoperoxidase, and secretory immunoglobulin A which can help clear pathogens from the child and benefit the child against infection.