secondary hyperaldosteronism

Secondary hyperaldosteronism, on the other hand, is due to overactivity of the renin-angiotensin system.

A secondary hyperaldosteronism develops due to the hypovolemia.

Also fibromuscular hyperplasia may cause secondary hyperaldosteronism.

Secondary hyperaldosteronism is often related to decreased cardiac output which is associated with elevated renin levels.

In secondary hyperaldosteronism, the excess aldosterone is caused by something outside the adrenal gland that mimics the primary condition.

Secondary hyperaldosteronism is generally related to high blood pressures, it also can be related to: cirrhosis of the liver, heart failure and nephritic syndrome.

When taking a blood test, the aldosterone-to-renin ratio is abnormally increased in primary hyperaldosteronism, and decreased or normal but with high renin in secondary hyperaldosteronism.

By hypersecretion of renin, JCT causes hypertension, often severe and usually sustained but occasionally paroxysmal, and secondary hyperaldosteronism inducing hypokalemia, though the later can be mild despite high renin.

Spironolactone is used primarily to treat heart failure, ascites in patients with liver disease, low-renin hypertension, hypokalemia, secondary hyperaldosteronism (such as occurs with hepatic cirrhosis), and Conn's syndrome (primary hyperaldosteronism).

Net secretion of potassium into a potassium free solution, also seen in this study, was not reversible by luminal SCFA, and may represent stimulation of active potassium secretion by secondary hyperaldosteronism in these patients.

Elevated renin due to renal artery stenosis or a very rare renin-producing juxtaglomerular cell tumor of the kidney can produce secondary hyperaldosteronism (as apposed to primary hyperaldosteronism aka Conn syndrome, usually due to a functional adrenal adenoma).