sclerosing agent

Sclerosing agents - These will harden the endothelial lining of vessels.

Some authors supported combined use of both agents with good results, while others found that a sclerosing agent does not improve haemostatic rates.

Its main effects are as an antiprotozoal, antirheumatic and an intrapleural sclerosing agent.

Controversy still exists concerning the need of sclerosing agents injection after epinephrine injection.

Treatments for removal of cystic hygroma are surgery or sclerosing agents which include:

With sclerotherapy, doctors inject a liquid chemical called a sclerosing agent directly into a varicose vein to close it off.

"All sclerosing agents are thought to work by ablating the endothelial cells of the disrupted lymphatics feeding into the lymphocele."

A sclerosing agent, such as 1% or 3% sodium tetradecyl sulfate, doxycycline, or ethanol, may be directly injected into a lymphocele.

As an intrapleural sclerosing agent, it is used as pneumothorax prophylaxis in patients at high risk of recurrence, e.g., cystic fibrosis patients.

It is possible that epinephrine can only temporarily stop bleeding and keep vessel existent, while a sclerosing agent can actually clot the vessel, and thereby decrease rebleeding.

Sterile Talc Powder, administered intrapleurally via a chest tube, is indicated as a sclerosing agent to decrease the recurrence of malignant pleural effusions in symptomatic patients.

The most effective sclerosing agent for malignant pericardial effusions had been tetracycline, with success rates of up to 80%;[6] however, this agent is no longer available as an intravenous drug in the United States.

Sterile Talc Powder is a sclerosing agent intended for intrapleural administration supplied in a single use 100 ml brown glass bottle, sealed with a gray, 20 mm stopper and covered with a flip-off seal.

A sclerosing agent, such as ethanolamine or absolute alcohol, is then injected into the varix to cause scarring and constriction of the varix with the aim of obliterating the varix (or varices).

Pure alcohol, by in situ tissue fixation and arterial compression, which causes arterial coagulation and tissue injury, is proved to be the most efficacious sclerosing agent in the arrest of arterial bleeding.

Liu G, Crump M, Goss PE, et al.: Prospective comparison of the sclerosing agents doxycycline and bleomycin for the primary management of malignant pericardial effusion and cardiac tamponade.

Limited case series suggest rates of pericardial fluid reaccumulation at 30 days ranging from 5% to 33% after pericardial drainage followed by intrapericardial treatment with sclerosing agents or phosphorus-colloid versus more than 50% of those treated with pericardial drainage alone.