I actually ruined my entire life in a sort of way.

You have no idea how many lives he could ruin, even in a couple of days!

But then they saw the hope and ruin in his eyes.

And he is poor to ruin them in this way.

"This project would really ruin any sense of living in the country."

If he ruined her career in this city, then what?

It would ruin the quality of health care in America.

The poor girl with a dead father and mother, ruined in the Depression.

Looking around, I noted that his house was being ruined in the process.

We know everything about everybody and can ruin a career in a matter of moments.