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In 1882 he first identified Klebsiella rhinoscleromatis, an organism that is the cause of rhinoscleroma.
Two unusual infections of note are from Klebsiella are rhinoscleroma and ozena.
Specific infections, such as syphilis, lupus, leprosy and rhinoscleroma, may cause destruction of the nasal structures leading to atrophic changes.
It is also an opportunistic pathogen for patients with chronic pulmonary disease, enteric pathogenicity, nasal mucosa atrophy, and rhinoscleroma.
Mikulicz's cells: Vesicular cells found in the diseased tissue in cases of rhinoscleroma and containing Klebsiella rhinoscleromatis.