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The majority of its resident proteins are retained within it through a retention motif.
Other proteins, however, constantly remain in the lumen and are known as endoplasmic reticulum resident proteins.
Golgi resident protein GCP60 is a protein that in humans is encoded by the ACBD3 gene.
Whether this has consequences for vesicle (or NAADP) function remains to be seen, but luminal pH is usually crucial for resident protein activity.
Retrieval (or retrograde) transport in COPI vesicles returns many of the lost ER resident proteins back to the endoplasmic reticulum.
ER retention refers to proteins that are retained in the endoplasmic reticulum, or ER, after folding; these are known as ER resident proteins.
SARAF is an endoplasmic reticulum (ER) membrane resident protein that associates with STIM1, to facilitate the inactivation of SOCE.
The phage genome is then transferred to the cytoplasm of the bacterial cell where resident proteins convert the single stranded DNA genome to a double stranded replicative form ("RF").
Endoplasmic reticulum resident protein 44 (ERp44) also known as thioredoxin domain-containing protein 4 (TXNDC4) is a protein that in humans is encoded by the ERP44 gene.
An example of an important endoplasmic reticulum resident protein is the chaperon protein known as BiP which identifies other proteins that have been improperly built or processed and keeps them from being sent to their final destinations.
Calreticulin also known as calregulin, CRP55, CaBP3, calsequestrin-like protein, and endoplasmic reticulum resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene.