renal clearance

Usually however, this technique only produces a slight increase in the renal clearance of the drug.

The parameter rclr is the free water concentration renal clearance.

The most likely way to leave the blood is via renal clearance and it will eventually leave the body in urine.

Cimetidine may reduce renal clearance of phenformin and increase lactic acidosis risk.

Renal clearance of pregabalin is 73 mL/minute.

Therefore the urinary and plasma concentrations of sodium must be compared to get an accurate picture of renal clearance.

Increased cardiac output by 30%--50% with concomitant increase in glomerular filtration rate and renal clearance.

Renal clearance is the volume of plasma from which the substance is completely cleared from the blood per unit time.

Certain drugs, such as thiazide diuretics, can increase uric acid levels in the blood by interfering with renal clearance.

Renal clearance, another consequence of their small size, is the reason for their short plasma half-life, generally a disadvantage for potential drugs.

Xipamide lowers the renal clearance of lithium which can lead to lithium intoxication.

Brinzolamide is excreted primarily unchanged (60%) in the urine, although the renal clearance rate has not been definitively determined.

Placental transfer of drugs, increased renal clearance, altered gastrointestinal absorption, and metabolism by the fetus might affect maternal drug levels.

Fractional excretion of other substances can be measured to determine renal clearance including urea, uric acid, and lithium.

The renal clearance ratio or fractional excretion is a measure of the speed at which a constituent of urine passes through the kidneys.

Given its renal clearance, LMWH may not be feasible in patients that have end-stage renal disease.

Although clearance may also involve other organs than the kidney, it is almost synonymous with renal clearance or renal plasma clearance.

But when bound to IGFBP-3, IGF-1 evades renal clearance.

Ciprofloxacin's renal clearance may affect other drugs subject to renal clearance or otherwise affecting the kidney.

Increased serum bilirubin increases renal clearance, decreases hepatic uptake and increases visualization time, thus a higher dose of 3 to 10 mCi is recommended.

Renal excretion occurs by both glomerular filtration and tubular secretion as evidenced by the high rate of renal clearance (approximately 275 mL/min).

Availability was severely limited, however, by the difficulty of manufacturing large quantities of penicillin and by the rapid renal clearance of the drug, necessitating frequent dosing.

Clearance can be determined on an overall, organism level ("systemic clearance") or at an organ level (hepatic clearance, renal clearance etc.).

The noticeably high serum pepsinogen I concentration in the patients with chronic renal failure is consistent with previous reports and can be explained by its impaired renal clearance.

How rapidly the kidney clears the blood plasma of a substance (be it water or solute) is the renal clearance, which is related to the rate of urine production.