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This assumption is consistent with recent direct measurements of regional perfusion and ventilation [ 52 53 ] .
The measurements were performed in the perfusion fluid obtained during regional perfusion of inflamed sigmoid and rectal segments.
During regional perfusion of defined sigmoid and rectal segments from healthy controls and patients with ulcerative colitis we were able to detect measurable amounts of myeloperoxidase.
This life-threatening syndrome is largely attributed to the cardiovascular abnormalities associated with septic shock, requiring supportive therapy (e.g. mechanical ventilation, fluid resuscitation, and vasopressors) with volume loading, oxygen delivery, and regional perfusion [ 8 ] .