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The Holmes Rebound phenomenon is a sign of cerebellar disease.
Rebound phenomena does not necessarily only occur on discontinuation of a prescribed dosage.
Typical parasymathetic rebound phenomena include:
These physiological mechanisms now seem fairly well understood, and underpin the contemporary use of hydrotherapy, with the reflex reactions described by some as the 'rebound phenomenon'
Long-term use of these medications is not recommended due to potential side effects, such as the rebound phenomenon (the original problem returns at a higher level), and the risk of developing a dependence on these drugs.
These results would suggest that loprazolam and possibly other benzodiazepines should be prescribed for 1 - 2 weeks rather than 2 - 4 weeks to reduce the risk of physical dependence, withdrawal, and rebound phenomenon.
The rebound effect, or rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage.
These medications, such as Ambien, Sonata, and Lunesta, are gaining popularity because they do not have a significant effect on the regular sleep cycle and are not associated with the rebound phenomenon seen with benzodiazepines.