radiosensitivity

The response of a cancer to radiation is described by its radiosensitivity.

Increases in radiosensitivity may increase the effectiveness of radiotherapy.

A third technique is to enhance the radiosensitivity of the cancer by giving certain drugs during a course of radiation therapy.

The increased radiosensitivity of certain organs in women, such as the breast, ovaries, and thyroid is likely the cause of this difference.

The traditional empiric therapy is irradiation, with the daily dose governed by the presumed radiosensitivity of the tumor.

All in all, the radiosensitivity of astroblastoma to therapy remains unclear, since some research advocate its effectiveness while others diminish the effects.

A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.

Panax notoginseng extract at a concentration of 0.1-100 mg/kg produced an increase in tumor radiosensitivity.

Radiosensitivity is the relative susceptibility of cells, tissues, organs or organisms to the harmful effect of ionizing radiation.

However, if the desired goal is increased radiosensitivity in a poorly oxygenated tumor, rather than directly killing the cells, then application of heat with every radiation treatment is acceptable.

Radiation exposure can cause cancer in any living tissue, but high-dose whole-body external exposure is most closely associated with leukemia, reflecting the high radiosensitivity of bone marrow.

A better understanding of the individual genetic determinants of radiosensitivity is fundamental to advances in personalized medicine and individualized application of radiation in diagnosis and treatment.

It is important to distinguish the radiosensitivity of a particular tumor, which to some extent is a laboratory measure, from the radiation "curability" of a cancer in actual clinical practice.

These syndromes share many features including cellular radiosensitivity, microcephaly and severe combined immunodeficiency (SCID) due to defective V(D)J recombination.

The risk of stochastic effects due to radiation exposure can be quantified using the effective dose, which is a weighted average of the equivalent dose to each organ depending upon its radiosensitivity.

Radiation dose to each site depends on a number of factors, including the radiosensitivity of each cancer type and whether there are tissues and organs nearby that may be damaged by radiation.

Wallace WH, Shalet SM, Hendry JH, et al.: Ovarian failure following abdominal irradiation in childhood: the radiosensitivity of the human oocyte.

It is also used as a radiosensitizer in adjunct to radiotherapies, since it can increase the radiosensitivity of tumor cells by inhibiting repair of sublethal radiation damage and delay the onset of the compensatory hyperplasia that occurs following irradiation.

Based on the identification of an altered regulation of vascular reactivity in tumors, the provascular approach aims at selectively inducing a transient dilation of functional tumor microvessels, leading to increased tumor perfusion, increased drug delivery and increased tumor oxygenation and radiosensitivity.

Because of the aggressive nature of MCC, its apparent radiosensitivity, and the high incidence of local and regional recurrences (including in-transit metastases after surgery alone to the primary tumor bed), some clinicians have recommended adjuvant radiation therapy to the primary site and nodal basin.