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Pyruvate decarboxylation requires a few cofactors in addition to the enzymes that make up the complex.
On entry to the mitochondria the pyruvate decarboxylation occurs, producing acetyl CoA.
This results in the production of acetyl CoA, which is the end goal of pyruvate decarboxylation.
Pyruvate decarboxylation by the pyruvate dehydrogenase complex produces acetyl-CoA.
In eukaryote cells the pyruvate decarboxylation occurs inside the mitochondria, after transport of the substrate, pyruvate, from the cytosol.
The pyruvate dehydrogenase complex is responsible for the pyruvate decarboxylation step that links glycolysis to the citric acid cycle.
As mentioned above, dihydrolipoyl transacetylase participates in the pyruvate decarboxylation reaction that links glycolysis to the citric acid cycle.
First, pyruvate is converted to acetyl-CoA and CO within the mitochondria in a process called pyruvate decarboxylation.
Acetyl-CoA is produced during the second step of aerobic cellular respiration, pyruvate decarboxylation, which occurs in the matrix of the mitochondria.
Pyruvate decarboxylation is also known as the "pyruvate dehydrogenase reaction" because it also involves the oxidation of pyruvate.
The pyruvate dehydrogenase complex contributes to transforming pyruvate into acetyl-CoA by a process called pyruvate decarboxylation.
In eukaryotes, pyruvate decarboxylation takes place exclusively inside the mitochondrial matrix; in prokaryotes similar reactions take place in the cytoplasm and at the plasma membrane.
The Link reaction, or pyruvate decarboxylation, forms an important link between the metabolic pathways of glycolysis and the citric acid or Krebs cycle.
This is the enzyme which catalyses Pyruvate decarboxylation, the reaction of Pyruvate with Coenzyme A and the major entry point into the TCA cycle:
Pyruvate dehydrogenase complex (PDC) is a complex of three enzymes that transform pyruvate into acetyl-CoA by a process called pyruvate decarboxylation.
CO is formed in Pyruvate decarboxylation, HO is formed in oxidative phosphorylation, and both are formed in the citric acid cycle.
In eukaryotes, glycolysis occurs in the cytoplasm, pyruvate decarboxylation in the mitochondria, the citric acid cycle within the mitochondrial matrix, and oxidative phosphorylation via the electron transport chain on the mitochondrial cristae.
Pyruvate decarboxylation (also known as the Swanson conversion, or oxidative decarboxylation reaction or link reaction) is the far from equilibrium biochemical reaction that uses pyruvate to form acetyl-CoA, releasing NADH, a reducing equivalent, and carbon dioxide via decarboxylation.