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He had even lost his knee-jerk and pupillary reflexes.
The variables most predictive of mortality were minimum systolic blood pressure, abnormal pupillary reflexes, and stupor/coma.
Patients may present with consciousness problems, headaches, nausea, visual defects, fatigue, disturbance of eye movements and pupillary reflexes, or coma.
While pupillary reflexes may be affected, these conditions generally do not cause a relative afferent pupillary defect.
Unfortunately, signs of elevated intracranial pressure such as papilloedema and loss of pupillary reflexes are not reliable and occur late in the disease process.
Neuro-ophthalmologists typically attend to diseases of the afferent visual system (most often involving the optic nerve), the efferent visual system (that controls eye movements), or the pupillary reflexes.