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In some cases, the cause of pulmonary alveolar proteinosis is unknown.
However, severe complications including pulmonary alveolar proteinosis and renal insufficiency may develop even with proper treatment.
Pre-existing pulmonary disease, especially pulmonary alveolar proteinosis, increases the risk of contracting a Nocardia pneumonia.
Pulmonary alveolar proteinosis is a rare disease in which a type of protein builds up in the air sacs (alveoli) of the lungs, making breathing difficult.
Trapnell BC, Nakata K, Kavuru MS. Pulmonary alveolar proteinosis syndrome.
Pulmonary alveolar proteinosis (abbreviated PAP), is a rare lung disease in which abnormal accumulation of surfactant occurs within the alveoli, interfering with gas exchange.
He was also one of the authors of the first case series on pulmonary alveolar proteinosis in a 1958 article in the New England Journal of Medicine (Rosen-Castleman-Liebow syndrome is a rarely-used term for that condition).