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Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid.
The synthesis of citrovorum factor by liver cells in culture was eventually accomplished from pteroylglutamic acid in the presence of suitable concentrations of ascorbic acid.
One needs biotin; another needs pteroylglutamic acid; still others need seventeen different amino acids supplied them as well as all the Vitamins B, but one (and yet it is popular and we cannot, with economic sense, abandon it)-" Byerley stirred in his seat, "To what purpose do you tell me all this?"