psammoma body

A psammoma body is a round collection of calcium, seen microscopically.

Psammoma bodies are commonly seen in certain tumors such as:

Somatostatinomas are associated with calcium deposits called psammoma bodies.

Psammoma bodies may be seen in:

Psammoma bodies usually have a laminar appearance, are circular, acellular and basophilic.

Papillary serous cystadenocarcinomas may exhibit psammoma bodies upon histopathology.

This mass can be seen microscopically, with the asbestos fiber layered by an iron-containing proteinaceous material (psammoma body).

This histology may be accompanied by psammoma body formation, which may result in a marked similarity with papillary carcinoma of the thyroid gland.

Characteristic Orphan Annie eye nuclear inclusions (nuclei with uniform staining, which appear empty) and psammoma bodies on light microscopy.

Endosalpingiosis is associated with the formation of psammoma bodies, which may lead to the misdiagnosis of malignancy, e.g. serous carcinoma.

Histologically, meningioma cells are relatively uniform, with a tendency to encircle one another, forming whorls and psammoma bodies (laminated calcific concretions).