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Then the protecting group is removed and the above steps are repeated.
At the end, all the protecting groups are removed.
Due to the possibility of unintended reactions, protecting groups are usually necessary.
The acetal is then called a protecting group for the carbonyl.
It is substantially more stable than other acyl protecting groups.
In synthetic organic chemistry the use of protecting groups is ubiquitous.
An example with dioxolane protecting group is given below.
This orthogonal protecting group strategy is common in organic synthesis.
Second, the protecting group must be able to withstand the conditions of solid-phase synthesis.
The light removes photoliabile protecting groups from the selected exposure areas.
This makes 2-mercaptoethanol useful as a protecting group.
The 1,3-dioxolane protecting group can thereafter be removed by further acid hydrolysis.
Methanesulfonates have been occasionally used as a protecting group for alcohols.
In vitro, protecting groups may be used during laboratory production of nucleotides.
For special applications like protein microarrays lithographic protecting groups are used.
This method eliminated the need for a protecting group or any other functionality at the end of the molecule.
He was the first to use the Carboxybenzyl protecting group for the synthesis of oligopeptides.
These protecting groups "lock" the sugars into a rigid chair conformation.
To furnish a functional oligonucleotide, all the protecting groups have to be removed.
Desilylation is also useful for the removal of silyl protecting groups.
Orthoesters are used in organic synthesis as protecting groups for esters.
The newly formed Cbz protecting group can be removed under reductive conditions.
In organic synthesis, the 2-tetrahydropyranyl group is used as a protecting group for alcohols.
It is a common protecting group for sugars and sugar alcohols, a simple example being solketal.
The acetonide protecting group was removed from the ketone.