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A follicle is an anatomical structure in which the primary oocyte develops.
These follicles each contain a similarly immature primary oocyte.
The primary oocyte is defined by its process of ootidogenesis, which is meiosis.
During oogenesis the oogonium becomes a primary oocyte.
During the primary oocyte stage of oogenesis, the nucleus is called a germinal vesicle.
The succeeding phase of ootidogenesis occurs when the primary oocyte develops into an ootid.
Thus, an immature ovum can spend up to 55 years as a primary oocyte (the last ovulation before menopause).
At puberty, one primary oocyte will complete meiosis to eventually form an ovum during each menstrual cycle.
As a result of meiosis I, the primary oocyte has now developed into the secondary oocyte and the first polar body.
The primary oocyte turns into a secondary oocyte in mature ovarian follicles.
In fact, a primary oocyte is, by its biological definition, a cell whose primary function is to divide by the process of meiosis.
The oocyte maturation inhibitor (OMI) is an inhibitory factor created by follicular cells during a primary oocyte maturation.
Included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte.
An important event in the development of the tertiary follicle occurs when the primary oocyte completes the first meiotic division, resulting in the formation of a polar body and a secondary oocyte.
"Intervention with the female parent is mechanically simpler because of larger cells-but involves a different problem; the primary oocyte must be encouraged, at point of meiosis, to produce two haploid and complementary secondary oocytes, rather than one oocyte and one polar body.
Until the preovulatory stage, the follicle contains a primary oocyte that is arrested in prophase of meiosis I. During the late preovulatory stage, the oocyte continues meiosis and becomes a secondary oocyte, arrested in metaphase II.