presynaptic membrane

After an action potential, Ca floods to the presynaptic membrane.

When an action potential invades the presynaptic membrane, these channels open and Ca enters.

They are located mostly on the presynaptic membrane and contain a single transmembrane domain.

An action potential reaches the presynaptic membrane, which changes the membrane polarisation.

All three effects increase the probability of neurotransmitter release from the presynaptic membrane, but the underlying mechanism is different for each.

Like most exocytosis, Ca regulates the release of vesicles from the presynaptic membrane.

Once the vesicle is in position it must wait until Ca enters the cell by the propagation of an action potential to the presynaptic membrane.

Finalized neurotransmitter vesicles are bound to the presynaptic membrane.

Another way is to measure vesicle fusion with the presynaptic membrane directly using a patch pipette.

The releasable pool is located in the active zone and is bound directly to the presynaptic membrane.

(ii) late steps of Ca evoked synaptic vesicle fusion with the presynaptic membrane.

The arciform density is located within the synaptic ridge, a small evagination of the presynaptic membrane.

TAAR1 is expressed near the presynaptic membrane.

Calcium ions flow through the presynaptic membrane, rapidly increasing the calcium concentration in the interior.

The pore increases in size until the entire vesicle membrane is indistinguishable from the presynaptic membrane.

The active zone is the portion of the presynaptic membrane opposite the postsynaptic density across the synaptic cleft.

This means that the synaptic vesicle fuses with the presynaptic membrane and releases its contents into the synapse.

Synaptotagmin is involved in the calcium-induced budding of vesicle containing neurotransmitters from the presynaptic membrane.

The release of neurotransmitter is accomplished by the fusion of neurotransmitter vesicles to the presynaptic membrane.

They hypothesized that at low frequencies of stimulation, most of the vesicles are quickly re-formed from the presynaptic membrane during and after stimulation.

Ribbon synapses contain a dense protein structure that tethers an array of vesicles perpendicular to the presynaptic membrane.

So training produces a brief change in the phosphorylation state of a specific presynaptic membrane protein, regulated by a specific protein kinase enzyme.

When stimulated, the taste bud triggers the release of neurotransmitter through exocytosis of synaptic vesicles from the presynaptic membrane.

Those vesicles in the ready-release pool reside very close to the presynaptic membrane and are primed to release neurotransmitters for nervous signal transduction.

After exocytosis, NRG1 is in the presynaptic membrane, where the ectodomain of NRG1 may be cleaved off.