Advice was sought from all chief administrative medical officers about the care of patients with presenile dementia.

Cases of the syndrome were first observed in three elderly female patients suffering from presenile dementia.

In the last few years of her life she had a disease which damaged her mind, called presenile dementia.

Psychoorganic syndrome is a progressive disease comparable to presenile dementia.

A speech given on 3 November 1906 was the first time the pathology and the clinical symptoms of presenile dementia were presented together.

Our rates of broad and probable Alzheimer's presenile dementia are minimum estimates of the true incidence.

Early Hurdles for Researchers The disease became known as Alzheimer's presenile dementia.

This information was requested from the registrar general wherever presenile dementia or Alzheimer's disease was a cause of death before the age of 73.

The second patient to undergo methylperone treatment was a 63-year-old woman with presenile dementia, which caused her to experience restlessness and paranoid hallucinations.

The final patient was a 69-year-old woman, diagnosed with presenile dementia after she expressing symptoms of memory dysfunction, depression and urinary incontinence.

Alzheimer is credited with identifying the first published case of "presenile dementia", which Kraepelin would later identify as Alzheimer's disease.

Later, family death certificates would name meningitis, Economo's disease, presenile dementia, leukoencephalitis, alcoholic encephalopathy and ictus.

The distinction between senile and presenile dementia is set at age 65 years, but some patients with presenile onset may not be admitted until after 65.

All 89 met study criteria for presenile dementia; nine of these records were of patients with probable Alzheimer's disease, but only three had not been admitted to a psychiatric hospital.

Attempts were also made to inoculate primates with tissues from people with a variety of other neurological diseases, including presenile dementia, mul-tiple sclerosis, Alzheimer's and Parkinson's disease.

The hospital records of 199 patients with presenile dementia who died in institutions other than psychiatric hospitals were requested but only 89 were located because over half of these records were destroyed after death.

A third observer (LJW) blindly examined a randomly chosen sample of 100 records of patients with presenile dementia, and interobserver reliability in the diagnosis of Alzheimer's disease was tested by Cohens κ statistic.

Gradually, though, scientists realized that the same plaques and tangles that appeared in the brains of people who died of presenile dementia were found in the brains of people with a later onset of the very same symptoms.

Oldendorf's experiments were also was the first to prove that cerebrospinal fluid functions as a "sink" in relationship to brain metabolism, a concept that is being investigated in relation to the pathophysiology of presenile dementias such as Alzheimer's disease.

Early in his career, Dr. Wisniewski, working closely with Dr. Robert Terry, observed that the neuropathological changes in presenile dementia, as Alzheimer's disease was known, were similar if not identical to those found in the senility of old age.

Alzheimer's presenile dementia is marked by deterioration of intellect, failure of memory and a striking appearance of rapid aging in a patient in middle life, symptoms that become progressively more severe over a period of just a few years and terminate in death.

While screening patients suspected of having Creutzfeldt-Jakob disease and other presenile dementias for mutations in the prion protein gene we identified a British patient with inherited prion disease (PrP lysine 200), which suggests a further focus of this disorder.

LEAD: Decades of studies among the Amish have helped to clarify and in some cases unveil the genetic bases for dozens of disorders, including cystic fibrosis, congenital cataracts, two types of dwarfism and a form of presenile dementia that resembles Alzheimer's disease.

Written by Dr Richard Mackarness, a psychiatrist at Basingstoke District Hospital, it described the good results of dietary change on a patient called 'Joanna' whose severe mental disturbance had been variously diagnosed as 'schizophrenia, schizo-affective psychosis, presenile dementia, temporal lobe epilepsy, neurotic depression and anxiety hysteria.'

We obtained data from the information and statistics division on all patients aged less than 73 years with a diagnostic code of Alzheimer's disease, senile dementia, presenile dementia, arteriosclerotic dementia, senile dementia with acute confusional state, or dementia unspecified attending all general psychiatric hospitals during 1974 to 1988.

This isn't a case of pre-senile dementia or anything like that.

Other doctors discovered similar abnormalities among patients in their 40's and 50's, so they long referred to Alzheimer's as "pre-senile dementia."

The ex-Guinness boss was let out of prison early after claiming he was suffering pre-senile dementia.

Some people with AIDS had been developing pre-senile dementia.

Saunders, who was released early, suffering pre-senile dementia, spoke on Wednesday evening at Cranfield School of Management in Beds.

Lord Justice Neill said that he was satisfied that Saunders was suffering from pre-senile dementia associated with Alzheimer's disease, which is incurable.

In 1835 she succumbed to a form of pre-senile dementia and for the last two decades of her life was confined to the house and terrace of Rydal Mount.

November 3 - A speech given by Alois Alzheimer for the first time presents the pathology and clinical symptoms of pre-senile dementia together; the condition will rapidly become known as Alzheimer's disease.

In Norway, studies suggest a possible link between high levels of aluminium in groundwater and senile dementia and Alzheimer's disease, a form of pre-senile dementia (sufferers are under 65 years old).

Second only to Alzheimer's disease (AD) in prevalence, FTD accounts for 20% of pre-senile dementia cases Symptoms can begin to appear on average around 45 to 65 years of age, regardless of gender.

Macrocephaly and ADHD are common among children, while pre-senile dementia, hydrocephalus (an abnormality of the dynamics of the cerebrospinal fluid), and urinary incontinence are symptoms for elderly patients (65 and older).