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It should have the ability to confer PTGS to a specific target.
PTGS was discovered in two ways.
As a PTGS, it is tested to confer viral resistance in plants.
This phenomenon is known as PTGS (for post transcriptional gene silencing)
Note that PTGS is often homozygosity-dependent [ 29 ] .
PTGS is now accepted as the plant equivalent of RNAi.
Transgene PTGS thus tapped into a preexisting natural mechanism for combating viruses.
PolyDNAvirus can also use PTGS to interfere with the host's gene expression.
A second study showed that plant RNA viruses could be both initiators and targets of PTGS.
Historically, it was known by other names, including co-suppression, post transcriptional gene silencing (PTGS), and quelling.
This dosage dependence of endogene silencing was the same as for the PTGS locus E82 (Fig.
Note that type L and type E loci did not lose their PTGS phenotype (Fig.
PTGS often leads to DNA methylation, although primarily in coding regions [ 35 ] .
PTGs are civilian-police SWAT units established to respond to high-risk situations which are beyond the scope or capacity of everyday policing.
Discussion The phenomenon of RNAi (or PTGS) is of great interest for two reasons [ 9, 10, 11, 12].
It remains untested whether the siRNA-mediated PTGS will work on mRNAs that never went through the nucleus.
PTGS was subsequently shown in 1997 to protect plants naturally from virus infection (Covey et al. 1997; Ratcliff et al. 1997).
Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the PTGS enzyme.
Since platelets have no DNA, they are unable to synthesize new PTGS once aspirin has irreversibly inhibited the enzyme, an important difference with reversible inhibitors.
This phenomenon has been referred to as post transcriptional gene silencing (PTGS) or RNA interference (RNAi).
Subsequent genetic studies showed that mutations in RDRP genes impaired PTGS in a variety of systems [ 25 38 51 52 ] .
PTGS and trans-silencing are similarly intertwined in other cases, for example in the epimutable petunia CHS41 locus [ 10 ] .
In line C73, the transition probably began in T2 seedlings, as suggested by the small fraction of adult T2 plants with a cop1-like PTGS phenotype.
Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase (COX), is the key enzyme in prostaglandin biosynthesis.
Both L91 and E82 are silenced posttranscriptionally (PTGS) and both are representative for a larger group of loci with similar transgene silencing characteristics.