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Skin changes including alopecia, vitiligo, and poliosis typically appear during this stage.
Poliosis is the greying of the hair.
Piebaldism is completely unrelated to acquired or infectious conditions such as vitiligo or poliosis.
Papilledema, secondary glaucoma, vitiligo, and poliosis of the eyelashes may accompany SO.
Poliosis is the decrease or absence of melanin (or color) in head hair, eyebrows, or eyelashes.
Chairman of the Institute of Trichologists Marilyn Sherlock said: "It's a genetic trait caused by Poliosis.
Several authors, including the Arabic doctor Mohammad-al-Ghâfiqî in the 12th century as well as Jacobi, Nettelship and Tay in the 19th century, described poliosis, neuralgias and hearing disorders.
White hair is a sign of age or genetics, which may be concealed with hair dye (not easily for some), although many prefer to assume it (especially if it is a poliosis characteristic of the person since childhood).
Davies became known for the white quiff of hair on his forehead (see Poliosis), and this became his trademark appearance, and was also much loved by TV comedy impressionists during his years on World of Sport.
Gray hair occurs when melanin production decreases or stops, while poliosis, typically in spots is hair (and often the skin to which the hair is attached) that never possessed melanin at all in the first place, or ceased for natural genetic reasons, generally in the first years of life.
Other skin features are not unique to individuals with TSC, including molluscum fibrosum or skin tags, which typically occur across the back of the neck and shoulders, café au lait spots or flat brown marks, and poliosis, a tuft or patch of white hair on the scalp or eyelids.