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To be absolutely certain of eradicating all the poliomyelitis virus in Cuba, he would need to burn the whole island to a cinder.
Over the next two years, at the University of Minnesota, he researched the effects of the poliomyelitis virus on the brain.
The Disease Polio, famous for withering limbs, is caused by the poliomyelitis virus.
Early exposure to the poliomyelitis virus, which was virtually universal before the age of modern plumbing, guaranteed the development of antibodies.
Except poliomyelitis viruses.
"A bomb exploding in a lab full of poliomyelitis virus would be the equivalent of a biological warhead detonating.
His isolation of the type MM poliomyelitis virus helped other scientists develope a vaccine, said Dr. George Irvin, professor of surgery at the University of Miami.
The three received the 1954 Nobel Prize in Physiology or Medicine "for their discovery of the ability of poliomyelitis viruses to grow in cultures of various types of tissue".
Their publication on the "Differentiation of Types of Poliomyelitis Viruses," in the American Journal of Hygiene in 1949 became a milestone in the development of new polio vaccine methods.
The germ proved to be a virus, although Flexner's discovery that antibodies, yet to be discovered, could successfully attack the disease would send research in the direction of finding a means of developing the immunization against the poliomyelitis virus.
He, John Franklin Enders and Frederick Chapman Robbins were awarded a Nobel Prize in Physiology or Medicine in 1954 for showing how to cultivate poliomyelitis viruses in a test tube, using tissue from a monkey.
Of course, the naturally occurring strains of an infectious disease could have been altered to make the microorganisms more stable, more virulent, or to overcome widespread immunity: years ago researchers produced a highly infective strain of poliomyelitis virus for just these reasons.
Information is not available, if anakinra would affect the rate of secondary transmission of vaccine virus (e.g., measles or poliomyelitis viruses) following administration of a live virus vaccine or regarding any other effect of vaccination on patients receiving the drug.
The Institute of Epidemiology and Preventative Medicine was established in 1946 and was instrumental in investigating the incidence of the Coxsackie virus (aseptic meningitis), poliomyelitis virus and was the first to isolate REO virus.
The institute has successfully produced the vaccines: BCG vaccine Danish Strain 1331 against tuberculosis, diTeBooster for revaccination, and VeroPol which is an inactivated poliomyelitis virus vaccine (IPV) that produces antibodies after primary vaccination for poliovirus 1, 2, and 3.