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After the baby's birth, the mother's placental hormones disappear and her blood sugars typically revert to normal.
Placental hormones, and to a lesser extent increased fat deposits during pregnancy, seem to mediate insulin resistance during pregnancy.
Since ST is a major source of placental hormones, which ensure optimal conditions for the fetus and mother, ERβ expression by ST may be involved in stimulation of placental hormonal production by estrogens.