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"What if there was a problem with placental blood flow just after birth?
The procedure worked in many cases, even when the placental blood was not perfectly matched to the patients' tissue.
Placental blood can take the place of bone marrow because it, too, is rich in stem cells.
It is a quirk of human biology that makes placental blood so rich in stem cells.
Identification of colchicine in placental blood from patients using herbal medicines.
Had they aspired, covered in placental blood, to grow into harmers, dark forces, life-enders?
But placental blood transplants can work when only 4 or 5 traits match, and sometimes even 3, though the odds of success increase with better matches.
As the pulmonary circulation increases there is an equivalent reduction in the placental blood flow which normally ceases completely after about three minutes.
Some placental blood may be returned to the neonatal circulation if the umbilical cord is not prematurely clamped.
(The researchers referred to it as placental blood, but it is widely known as cord blood.)
Oxygenated blood now stimulates constriction of the umbilical arteries resulting in a reduction in placental blood flow.
The great advantage of placental blood, he said, is that it does not have to be as closely matched to the recipient's tissue as bone marrow does.
Placental blood harvested from a baby's umbilical cord is a rich source of stem cells, which generate the bone marrow that produces mature blood cells.
Immediate cord clamping may deprive the infant of placental blood, and previous reports suggest that a long delay may lead to adverse effects due to hypervolaemia.
Cord blood is the blood contained in the placental blood vessels and umbilical cord, which connects an unborn baby to the mother's womb.
Among the advantages that placental blood has over bone marrow, Dr. Rubinstein said, the most important is that it is easier to match donors and recipients.
The core of placental villi contain mesenchymal cells and placental blood vessels that are directly connected to the fetal circulation via the umbilical cord.
Some of it was fresh blood, some of it was old and slow-flowing, some of it was placental blood.
For example, if there was a problem with placental blood flow before or during birth, couldn't it cause a loss of oxygen in the fetus, which would show up in the autopsy?"
Holding the infant 20 cm below the introitus for 30 seconds before clamping the cord probably enables an intermediate and beneficial volume of placental blood to enter the fetal circulation.
The ductus venosus carries blood from the left portal vein to the left hepatic vein and then to the inferior vena cava, allowing placental blood to bypass the liver.
Preserving stem cells from umbilical cord blood is a significant investment, and preserving the much larger amount of stem cells that are available from placental blood is an additional cost.
Dr. Cagnacci speculated that infections that had a seasonal pattern might also affect the fetus and that temperature might play a role by altering placental blood flow at critical periods of development.
It is believed that this correlation between handedness in twins mirror imaging is due to MZ twins sharing the same placental blood supply, and being surrounded by the same chorionic membrane.
The American Academy of Pediatricians notes: "if cord clamping is done too soon after birth, the infant may be deprived of a placental blood transfusion, resulting in lower blood volume and increased risk for anemia".