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Pharmacological cardioversion is an especially good option in patients with fibrillation of recent onset.
There are various classes of agents that are most effective for pharmacological cardioversion.
Drugs that are effective at maintaining normal rhythm after electric cardioversion, can also be used for pharmacological cardioversion.
The anti-arrhythmic medications often used in either pharmacological cardioversion or in the prevention of relapse to AF alter the flux of ions in heart tissue, making them less excitable, setting the stage for spontaneous and durable cardioversion.