peritumoral

Swelling around the tumor known as peritumoral edema can also show a similar result.

The T1 and T2 relaxation times are increased in cerebral tumors and peritumoral tissue compared with normal brain.

Oncomatryx's research focuses on peritumoral stroma, which has been found to take part in promoting cancer invasiveness and curtailing treatment efficacy.

Adjacent cord edema and syringomyelia and peritumoral cysts may be present in addition to reactive scoliosis.

CS treatment often is required to control symptoms related to increased intracranial pressure (ICP) or peritumoral edema.

Antitumor drugs developed by Oncomatryx, which specifically target the peritumoral stroma, are currently in pre-clinical development phase and will enter clinical trials in 2015.

Overstaging by endorectal sonography has been reported in approximately 10% of patients and is thought to result from peritumoral inflammation at the leading edge of the tumor.

Biological response modifiers such as cytokines and growth factors released in peritumoral tissues, perhaps by the neoplastic cells themselves, may well be implicated in their activation.

Elevated levels of Peritumoral chondroitin Sulfate are Predictive of poor prognosis in patients treated by Radical Prostatectomy for early stage prostate cancer.Ricciardelli C et al.

This gene is expressed in colorectal and breast carcinomas but not in normal colon, mammary gland, or peritumoral tissues, suggesting a possible role for this gene in tumor processes.

Sioutos P, Carter LP, Weinand ME, Hamilton AJ, Nees J, Orozco J: Intraoperative measurement of peritumoral regional cortical cerebral blood flow.

Corticosteroids, usually dexamethasone given 4 to 8 mg every 4 to 6 h, can reduce peritumoral edema (through rearrangement of the blood-brain barrier), diminishing mass effect and lowering intracranial pressure, with a decrease in headache or drowsiness.

These immunotoxins and ADCs are specifically directed against two proteins, known as MTX1 and MTX2, which are expressed only in the peritumoral stroma that surround the tumor and facilitates its progression and metastasis.

Oncomatryx and its collaborators and advisors have proved that peritumoral stroma, which is constituted by mesenchymal cells and extracellular matrix, plays a key role in tumor invasiveness and metastasis, at the same time being a physical barrier that prevents anti-cancer agents from reaching tumor cells.