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Transmission of Oesophagostomum is believed to be oral-fecal for both humans and animals, largely because percutaneous infection with Oesophagostomum has never been reported.
In previously sensitised dogs, skin reactions such as moist eczema and ulceration at the sites of percutaneous infection occur especially affecting the inter-digital skin.
In percutaneous infection, larvae migrate via the blood stream to the lungs where they moult to L4 in the bronchi and trachea, and are then swallowed and pass to the small intestine where the final moult occurs.