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Acquired pendular nystagmus is seen in a variety of conditions with the two most frequent being multiple sclerosis and oculopalatal tremor.
A deficit in this fixation system results in ocular instability that mainly leads to acquired pendular nystagmus and saccadic intrusions.
There is some evidence of benefit in acquired pendular nystagmus and infantile nystagmus but not in periodic alternating nystagmus.