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However, a thymic biopsy may be necessary to make the pathologic diagnosis.
"Well, in the end, it's still a pathologic diagnosis.
These differences probably reflect some biological differences as well as differences in pathologic diagnosis and reporting.
The AFIP played a critical role in the standardization of pathologic diagnosis of tumors.
Studies suggest that selected presumed neuroblastomas detected in infants by screening may be safely observed without surgical intervention and without pathologic diagnosis.
Despite all of these evaluations, however, the majority of patients with PCNSL require a pathologic diagnosis.
Because of the debate and difficulty of staining, pathologic diagnosis often requires morphologic, cytochemical and electron microscope analysis as well.
Most tumor banks collect their tumor samples from discarded tissues not needed for pathologic diagnosis, after patients undergo surgery to remove the tumor.
The most common pathologic diagnosis in this instance is Hodgkin lymphoma or non-Hodgkin lymphoma, with CUP being less frequent.
Although a pathologic diagnosis of UIP often corresponds to a clinical diagnosis of IPF, it can be seen in other diseases as well.
This further complicates the distinction between a clinical diagnosis of a KA and the pathologic diagnosis of a KA vs a squamous cell cancer.
Nucleic acid-based tests, such as in situ DNA hybridization and PCR, are important for pathologic diagnoses in biologic specimens.
For well- or moderately differentiated tumors, the pathologic diagnosis of an epithelial cancer versus lymphoma, sarcoma, melanoma, or a germ cell tumor, for instance, is often readily apparent.
An unequivocal pathologic diagnosis made from tumor tissue by light microscopy (with or without immunohistology, electron microscopy, or increased levels of serum catecholamines or urinary catecholamine metabolites).
Diagnosis requires clinical findings compatible with interstitial lung disease in combination with either characteristic radiologic findings or a pathologic diagnosis of UIP on surgical lung biopsy.
Tumor handling After the gross pathologic diagnosis was completed, the remaining portion of each tumor used in the present study was snap frozen in liquid nitrogen and placed in a freezer at -80 C until use.