paratuberculosis

Seven of the 31 cultures were positive for M paratuberculosis.

The macrophage can control growth and even kill M. paratuberculosis.

In cattle, the main signs of paratuberculosis are diarrhea and wasting.

Once the symptoms appear, paratuberculosis is progressive and affected animals eventually die.

These cell biology studies clearly add to our understanding of M. paratuberculosis interactions with macrophages.

It has demonstrated some in vitro effectiveness against Mycobacterium paratuberculosis.

Johne's disease, a paratuberculosis disease of cattle he described in 1895, is named for him.

Note the electron transparent lipid vesicles present within M. paratuberculosis.

At present Mycobacterium paratuberculosis is the favoured candidate.

There appears to be a tenuous relationship to gain control between M. paratuberculosis and the macrophage with survival at stake.

It is caused by the bacterium Mycobacterium avium subspecies paratuberculosis.

This is clearly not the case for M. paratuberculosis or other mycobacteria as they remain morphologically similar at least up until 4 days postinfection.

The significance of separate M. paratuberculosis -containing vacuoles observed in this study is still unclear.

The positive non-inflammatory bowel disease culture also grew acid fast bacilli which were not M paratuberculosis.

In deer, paratuberculosis can progress rapidly.

This study has also provided a general description of early events in M. paratuberculosis infection of cultured macrophages.

Several studies surrounding the interactions of M. paratuberculosis with macrophages have been published because of its importance in pathogenesis.

However, there appear to be no notable differences between M. avium and M. paratuberculosis at this level.

The pathogenicity of Mycobacteria paratuberculosis remains uncertain.

The specificity of IS900 polymerase chain reaction for M paratuberculosis has already been shown.

The cell counts from three independent experiments showed a slow decline in M. paratuberculosis viability over 7 days (Fig.

Elsaghier and colleagues explored a possible role for M paratuberculosis in the pathogenesis of Crohn's disease.

It is often abbreviated M. paratuberculosis or M. avium ssp.

Therefore rabbit antibodies against a whole cell sonicated lysate of M. paratuberculosis were affinity purified.

Progress on these research fronts will improve our chances of understanding and controlling infections caused by M. paratuberculosis and related pathogens.