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The basilar membrane is made up of some 24,000 parallel fibers stretching across its width.
Bundles of parallel fibers can be used to illuminate and observe hard-to-reach places.
Granule cells have axons which rise up and then branch out into parallel fibers.
Parallel fibers arise from granule cells in the cerebellar cortex.
It is a band of parallel fibers that is found in felines but not in humans.
The axon ascends into the molecular layer where it splits to form parallel fibers.
The vast majority of granule cell axonal synapses are found on the parallel fibers.
Their large dendritic arbors form nearly two-dimensional layers through which parallel fibers from the deeper-layers pass.
Thus, the dendrites of a Purkinje cell form a dense planar net, through which parallel fibers pass at right angles.
Parallel fibers are said to be responsible for the simple (all or nothing, amplitude invariant) spiking of the Purkinje cell.
Both parallel fibers and climbing fibers must be simultaneously activated for LTD to occur.
LTD in the cerebellum requires a coincident stimulation of parallel fibers and climbing fibers.
Purkinje cells send the inhibitive information by obtaining learning information from parallel fibers of granule cells.
In comparison, the cerebellar granule cell axon is characterized by a single T-shaped branch node from which two parallel fibers extend.
The initial memory trace is thought to form here and then travel outwards to other brain nuclei for consolidation via parallel fibers known as Purkinje cells.
Fan-shaped muscles, such as the pectoralis major in humans, have a weaker pull on the attachment site compared to other parallel fibers due to their broad nature.
These cells receive information through extensive apical dendritic projections from parallel fibers that signal the transmission of an order to release an EOD.
Its axon projects to the molecular layer of the dorsal cochlear nucleus where it forms parallel fibers, also similar to cerebellar granule cells.
These parallel fibers form thousands of excitatory Granule-cell-Purkinje-cell synapses onto the dendrites of Purkinje cells.
The parallel fibers and ascending axon synapses from the same granule cell fire in synchronisation which results in excitatory signals.
Glutamate released from the parallel fibers activates AMPA receptors which depolarize the postsynaptic cell.
They receive excitatory input from mossy fibres, also synapsing on granule cells, and parallel fibers, which are long granule cell axons.
The parallel fibers also activate metabotropic glutamate receptors that release the second messengers IP and DAG.
The protein is a major component of the intermediate filament network in small interneurons and cerebellar granule cells, where it is present in the parallel fibers.
With the loss of AMPA receptors, the postsynaptic Purkinje cell response to glutamate release from parallel fibers is depressed.
The essential feature of worsted yarn is straight, parallel fibres.
It is arranged in bundles of parallel fibres.
Climbing and parallel fibres must be activated together to depolarize the Purkinje cells while activating mGlur1s.
There are several sources of calcium signaling that elicit LTD: climbing fibres and parallel fibres which converge onto Purkinje cells.
The synaptic spines on the Purkinje cells, which receive the input from the parallel fibres, contains an ER system rich in IP 3 Rs.
While working with the cerebellum, Kreitzer's group also discovered that depolarization of Purkinje cells could also cause a temporary reduction in excitatory input into these cells from both climbing fibres and parallel fibres (Kreitzer et al. 2001b).
In the parallel fibres, GluRs are activated by constant activation of the parallel fibres which indirectly induces the IP3 to bind to its receptor (IP3) and activate calcium release from intracellular storage.