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The papillary dermis is the uppermost layer of the dermis.
Level II: Invasion of the papillary dermis but does not reach the papillary-reticular dermal interface.
Microscopically, the vesicles in lymphangioma circumscriptum are greatly dilated lymph channels that cause the papillary dermis to expand.
Skin biopsies reveal a dense lymphohistiocytic infiltrate, eosinophils in the papillary dermis, and increased Langerhans cells (S-100 positive).
Excoriation - a punctate or linear abrasion produced by mechanical means (often scratching), usually involving only the epidermis, but commonly reaching the papillary dermis.
Level III: Invasion fills and expands the papillary dermis but does not penetrate the reticular dermis.
The superficial papillary dermis interdigitates with the overlying rete ridges of the epidermis, between which the two layers interact through the basement membrane zone.
The fibers of the upper dermis ("papillary dermis") are thinner than the fibers of the deep dermis, thus the skin envelope is 1-3 mm thick.
Beneath the lamina densa, loop-structured, cross-banded anchoring fibrils extend more than 300 nm beneath the basement membrane within the papillary dermis.
When the tumor cells start to move in a different direction - vertically up into the epidermis and into the papillary dermis - the behaviour of the cells changes dramatically.
The dermis is the layer of skin between the epidermis and subcutaneous tissue, and comprises two sections, the papillary dermis and the reticular dermis.
Familial myxovascular fibromas present with multiple verrucous papules on the palms and fingers, which on biopsy show focal neovascularization and mucin-like changes in the papillary dermis.
The reticular dermis is the lower layer of the dermis, found under the papillary dermis, composed of dense irregular connective tissue featuring densely packed collagen fibers.
These antibodies cross-react with eTG, and IgA/eTG complexes deposit within the papillary dermis to cause the lesions of dermatitis herpetiformis.
Histopathologic features include perifollicular lymphocytic infiltrate, concentric lamellar fibrosis (layers of fibroblast in papillary dermis), sebaceous gland loss and premature disintegration of the internal root sheath.
The dermal papillae are part of the uppermost layer of the dermis, the papillary dermis, and the ridges they form greatly increase the surface area between the dermis and epidermis.
The SAMPUS category includes certain atypical junctional melanocytic proliferations and proliferations in both the epidermis and papillary dermis that are not accompanied by intradermal tumorigenic architecture or cell mitosis.
It has also been proposed that the distribution of affected blood vessels - predominantly in the superficial subcutaneous plexus (found in the papillary dermis)- results in the net-like pattern of erythema ab igne skin lesions.
As the condition becomes more established, the collagen fibers of the papillary dermis and reticular dermis become increasingly replaced by thickened and curled fibers that form tangled masses and appear basophilic under routine haematoxylin and eosin staining.
One is the papillary layer which is the superficial layer and consists of the areolar connective tissue.
This epithelium contains eleidin which is transparent and the blood vessels are near the surface of the papillary layer, revealing the 'red blood cell' color.
The deep network lies between the dermis and the subcutaneous tissue, while the shallow network lies within the papillary layer of the dermis.
Therefore, the epithelium immediately above the putative stem cells in the papillae may be much thinner than that above the daughter cells in the inter papillary layer (the opposite to the skin).
The basal cells in the stratum basale of the epidermis connect to the basement membrane by the anchoring filaments of hemidesmosomes; the cells of the papillary layer of the dermis are attached to the basement membrane by anchoring fibrils, which consist of type VII collagen.