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This study illustrates that the outer hair cells are related to tinnitus.
When only the outer hair cells are damaged the filter is broader on the low frequency side.
Specifically, noise damage typically damages the first layer of the outer hair cells.
A movie clip showing an isolated outer hair cell moving in response to electrical stimulation can be seen here.
Outer hair cells extend the hearing range to about 200 kHz in some marine mammals.
The expression pattern correlates with the appearance of outer hair cell electromotility.
Outer hair cells have evolved only in mammals.
Outer hair cells on the other hand boost the mechanical signal by using electromechanical feedback.
One of his contributions to the field was the observation of electromotility in outer hair cells.
It is dominated by the outer hair cells of the organ of corti.
Type II neurons on the other hand innervate outer hair cells.
Within this organ are specialized cells, "outer hair cells," that may be the key to the mystery.
Outer hair cells are a motor structure.
However, as in the base, afferents and efferents extend sparingly to the outer hair cell region.
Only an occasional fiber extends beyond the inner spiral bundle into the area of the outer hair cells (Fig.
Interestingly, the growth to outer hair cells is most affected in Brn3c null mutant cochleae.
In mammalian outer hair cells, the receptor potential triggers active vibrations of the cell body.
The outer hair cells feed back energy to amplify the traveling wave, by up to 65 dB at some locations.
His research interests include the mechanics of hearing, and the molecular basis of cochlear outer hair cell function.
The development of outer hair cells in the cochlea may therefore have been a major step in the evolution of humans.
At the opposite basilar pole, the outer hair cells are firmly held by the phalangeal cells.
The organ of Corti vibrates due to outer hair cells further amplifying these vibrations.
Prestin densely lines the lipid bilayer of the outer hair cell membranes.
These data suggest that fiber organization in the outer hair cell region is partly disrupted in Brn3c null mutant.
However, no fibers extend to the outer hair cell region in Brn3c null mutants (Figs.