osteocyte

Even though the function of the osteocyte is still under investigation, there are some ideas on what they might do.

The space that an osteocyte occupies is called a lacuna (Latin for a pit).

Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation.

A lacuna never contains more than one osteocyte.

When the osteoblast becomes trapped, it becomes known as a osteocyte.

Most of the receptor activities that play an important role in bone function are present in the mature osteocyte.

The osteocyte lies within a small chamber called a lacuna, which is within the bone matrix.

Finally, it is believed that the osteocyte might compensate for he strain on the bone due to their many arms which extend out to other osteocytes.

Each lacuna is occupied during life by a branched cell, termed an osteocyte, bone-cell or bone-corpuscle.

One function of the osteocyte might be the remodeling of the bone through growths of new arms on the cell.

An osteocyte, a star shaped cell, is the most commonly found cell in mature bone, and can live as long as the organism itself.

A mature osteocyte contains a single nucleus that is located toward the vascular side and has one or two nucleoli and a membrane.

The osteocyte is an important regulator of bone mass and a key endocrine regulator of phosphate metabolism.

Rouget-Neumann sheath: Uncalcified bone matrix between an osteocyte and the lacunar or canalicular wall.

In histology, a lacuna is a small space containing an osteocyte in bone or chondrocyte in cartilage.

The osteocyte is still a mysterious cell, in the way that biologists still have not figured out the true function of the osteocyte.

When the osteoblast is transformed into an osteocyte, the transformation causes the osteocyte to loose a majority of its organelles.

Once an osteoblast creates the new bone around itself, it is trapped and can no longer move or form bone; this is how an osteocyte is created.

Recent research advocates that the minute spaces within the substance of the core, which have long been known to exist, are true bone cell or osteocyte cell spaces.

It is decreased by high levels of serum phosphate and by an increase in the production of the hormone FGF-23 by osteocyte cells in bone.

Skeletal unloading has been shown to induce osteocyte hypoxia in vivo, this is when osteocytes undergo apoptosis and recruit osteoclasts to resorb bone.

Matrix extracellular phosphoglycoprotein (Osteoblast/osteocyte factor 45) is a protein that in humans is encoded by the MEPE gene.

As the osteoblast transitions to an osteocyte, alkaline phosphatase is reduced, and casein kinase II is elevated, as is osteocalcin.

During bone formation, an osteoblast is left behind and buried in the bone matrix as an "osteoid osteocyte", which maintains contact with the osteoblasts through extending cellular processes.

This led to increased mineralization and expression of osteocyte markers, supporting the data showing that loss of heparan sulfate at the COJ is a key factor in osteogenesis.