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Finally, an organ-specific immune response is not seen in any other kind of venous disease.
Deposition can be systemic (affecting many different organ systems) or organ-specific.
Floxed genes can also be used to produce organ-specific knockouts.
The organ-specific expression pattern of these genes may spark interest in defining their physiological functions.
It is an organ-specific antigen in the gut.
This led to the concept of organ-specific auto-immunity.
These are candidate tissue- or organ-specific genes.
This may lead to organ-specific autoimmune disease.
Other examples of organ-specific radiopharmaceuticals include:
Up until a decade ago, the classic paradigm of wound healing, involving stem cells restricted to organ-specific lineages, had never been seriously challenged.
In tissues, organ-specific macrophages are differentiated from phagocytic cells present in the blood called monocytes.
Plating of hepatocytes with other organ-specific cells allows evaluation of drug metabolism and organotoxicity.
More recent research has examined oxygen delivery in trauma patients, looking at biomarkers and physiological parameters such as organ-specific pH monitoring.
At present, it is not obvious how disruption of a basic cellular process causes the tissue- and organ-specific manifestations seen in SDS.
PSA, an organ-specific marker with greater sensitivity and high specificity for prostate tissue, is often used as a tumor marker.
Organ-specific anatomic considerations also influence metastasis; these include blood-flow patterns from the primary tumor and the homing ability of cancer cells to certain tissues.
Autoimmune diseases can be broadly divided into systemic and organ-specific or localised autoimmune disorders, depending on the principal clinico-pathologic features of each disease.
On a genome scale, pronounced tissue- and organ-specific and developmental expression patterns of S/MAR-containing genes have been detected.
Autoimmune Diseases And Treatment : Organ-specific And Systemic Disorders.
During organogenesis, molecular and cellular interactions between germ layers, combined with the cells' developmental potential, or competence to respond, prompt the further differentiation of organ-specific cell types.
Tumor M2-PK can be elevated in many tumor types, rather than being an organ-specific tumor marker such as PSA.
Finally, it has been shown that dysregulated T cells can cause systemic autoimmunity and auto-antibody production or contribute to T cell-mediated organ-specific autoimmunity.
Organ-specific effects to a larger degree depend on the zone of action and low-frequency modulation of EMI EHF range.
Current DBPs include gene fusion in cancers, major organ-specific complications of diabetes, nutrition and obesity, and co-morbid disease associations of bipolar disorder.
The differences in risk are even greater when considering organ-specific cancers, especially given that both reports identify breast, ovarian, lung, colon, and thyroid tissues as the most radiosensitive among women.