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There is a central depression, of variable size, called the optic cup.
Lens pits and optic cups form the start of the developing eye.
Iris is formed from the optic cup cells.
The cupula optica, or optic cup, in embryological development of the eye.
The optic cup also produces the iris sphincter and dilator muscles.
The optic cup is the white, cup-like area in the center of the optic disc.
The eye field gives rise to the optic vesicle and then to the optic cup.
The iris develops from the anterior two layers of an embryonic neuroectoderm structure called the optic cup.
Obliteration of the optic cup.
Despite their very different functions and histological appearances, these regions have a common origin from the two layers of the embryological optic cup.
Optic cup may refer to:
A central core of white glial tissue occupies the position of the normal optic cup, causing a white mass.
Optic cup (embryology)
The optic cup then delaminates into two layers: The neural retina and the retinal pigment epithelium.
The fgf8 mRNA becomes localized in what differentiates into the neural retina of the optic cup.
After the migrating mesenchymal cells reach the anterior margin of the developing optic cup they must form the tissues of the iridocorneal angle.
By E16.5 the anterior margin of the optic cup had extended more anteriorly but no obvious differentiation into the iris and ciliary body had occurred.
These are not derived from the neural crest, instead an outpouching of the neural tube generates the optic cup which, in turn, forms the retina.
The ratio of the size of the optic cup to the optic disc (or cup-to-disc ratio) is measured to diagnose glaucoma.
Invagination of the optic vesicle to form the optic cup occurs around E10, as the lens vesicle is developing [ 22].
In the past, scientists have gotten animals like amphibians to grow eyes on various parts of their body by transplanting the entire embryonic optic cup from one spot to another.
The optic disc originates from the optic cup when the optic vesicle invaginates and forms an embryonic fissure (or groove).
Shortly after the stalk of the lens vesicle disappears at E10.5, a few undifferentiated mesenchymal cells were present adjacent to the anterior margin of the optic cup.
Briefly, in mice, migrating mesenchyme begins to fill the space between the anterior edge of the optic cup, the surface ectoderm and the lens vesicle at E11 to E12.
The lens acts as an inducer back to the optic vesicle to transform it into the optic cup and back to the ectoderm to transform it into the cornea.