The next generation product Omnipaque made the company highly successful.

Omnipaque 350 is commonly used as a contrast agent during coronary angiography.

The increases for Omnipaque, of about 10 percent, do not reflect the full amount of the anti-dumping duties in the selling price to the purchaser.

Sales of Omnipaque, the world's best selling non-ionic X-ray diagnostic product, increased by four per cent to £183 million.

Nycomed's Omnipaque was introduced into the Canadian market in 1985, followed by imports of Visipaque in 1994.

Hafslund Nycomed has about 40 percent of the $1.04 billion American market for X-ray imaging agents, notably Omnipaque.

A very similar product also manufactured by GE Healthcare is Omnipaque (Iohexol as the main drug substance).

Its best-selling prescription drug is Omnipaque, which highlights body organs during X-rays and CAT scans.

Nycomed sells Omnipaque and Visipaque, a non-ionic monomer and a non-ionic dimer respectively.

The company's brand names also include Midol, Panadol, Lysol and Omnipaque, an injectible dye for use in making X-rays.

Competing products are made by the Squibb Corporation, which produces Isovue, and Sterling Drug Inc., which makes Omnipaque.

Omnipaque's closest competitor, Isovue made by Bristol-Myers Squibb, will be faced with generic competition after Jan. 1 when its patent expires.

Omnipaque became a so-called "blockbuster" pharmaceutical with end-user sales of over $1 billion a year and was for many years ranked among the top 10 pharmaceutical products sold world-wide.

The Bracco product is marketed under the trade name of Isovue while the Nycomed products are marketed under the trade names of Omnipaque and Visipaque.

(Searle), based in Barceloneta, Puerto Rico, has produced Omnipaque and Visipaque for the Canadian market under a tolling arrangement with Nycomed Imaging AS.

Iohexol is a contrast agent, sold under the trade names Omnipaque and Exypaque; this compound is also sold as a density gradient medium under the names Accudenz, Histodenz and Nycodenz.

In the Tribunal's view, the price for Omnipaque, the most popular brand in the domestic market, would need to increase much more than it already has to reflect the anti-dumping duties in the full amount as required by SIMA.

Sterling said its domestic sales of pharmaceutical specialties in the second quarter increased 15 percent from a year earlier, largely as a result of the continued success of Omnipaque, a non-ionic diagnostic agent for use in a range of radiographic procedures.

Buyers testified that cutting other items in the current budget might enable them to accommodate the recent increases in the price for Nycomed's Omnipaque, but that cutting these other items would put some other aspect of patient care at risk.

Export Price In its complaint, MMI estimated the export prices for each of the three imported goods, Isovue, Omnipaque and Visipaque, for a 100 ml bottle with an iodine concentration of 300 I mg/ml.

Patents for Isovue and Hexabrix expired in 1996 and 1997 respectively, while patents for Omnipaque, Visipaque and Ultravist expired in 1999.8 Only Osmovist and Optiray are still under patent in Canada.

Searle Ltd., Barceloneta, Puerto Rico Searle Ltd., Puerto Rico, is the manufacturer and exporter of the subject contrast media marketed by the Nycomed group under the brand names Omnipaque and Visipaque.

In terms of the molecular structure of the iodine powder used in their manufacture, LOCM may be non-ionic monomers, ionic dimers or non-ionic dimers.4 Omnipaque, Optiray, Isovue and Ultravist are non-ionic monomers.

Nycomed indicated at the hearing that some purchasers might tolerate a price increase of 5 percent before they considered switching supplier, but that anything over 5 percent would cause significant problems.36 Nycomed also referred to the recent increase of about 10 percent applied to Omnipaque after the injury finding.

The subject goods are marketed by the Bracco group of companies under the brand name Isovue, by Mallinckrodt Inc., under the brand names Optiray and Hexabrix and by the Nycomed group of companies under the brand names Omnipaque and Visipaque.