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Recovery following peripheral destruction of olfactory neurons in young and adult mice.
Olfactory neurons differ from one another by the nature of the receptor that they possess.
Later arr1 and arr2 were found to play an important role in olfactory neurons and renamed "sensory".
Olfactory neurons transduce receptor activation into electrical signals in neurons.
It is involved in the regulation of male courtship behaviour, this may be via olfactory neuron mediated regulation.
These data suggest that the olfactory neurons can respond to PN-1 directly or to changes in the local environment caused by PN-1.
These substances are detectable by olfactory neurons in concentrations as low as 10 parts per billion, hydrogen sulfide being the most detectable.
During development, primitive olfactory neurons extend their axons from the olfactory placode, through the mesenchyme, towards the telencephalic vesicle.
Variable expression of Robo receptors on Drosophila olfactory neurons controls axonal organization in the olfactory lobes.
OEG are thought to be in part responsible for the neurogenesis of primary olfactory neurons through the processes of fasciculation, cell sorting, and axonal targeting.
Each olfactory neuron appears to express a single type of OR [ 8, 9, 10] implying a sophisticated mechanism of OR gene choice.
The complex set of olfactory receptors on different olfactory neurons can distinguish a new odor from the background environmental odors and determine the concentration of the odor.
Receptors on hairlike cilia convey the odor molecules' message to olfactory neurons, which send it to the areas of the brain that distinguish odors and relate them to other senses.
The mucus overlying the epithelium contains mucopolysaccharides, salts, enzymes, and antibodies (these are highly important, as the olfactory neurons provide a direct passage for infection to pass to the brain).
But, he pointed out, olfactory neurons, unlike those in other areas of the brain, die and are replaced throughout life, displaying a plasticity that makes the olfactory system relatively resistant to degenerative disease.
Activity-dependent processes may therefore be essential for the survival of the olfactory neurons postnatally, and in that manner, may alter the input to individual glomeruli, altering the sensitivity to individual odors.
The peripheral explanation of this disorder is that the rogue neurons malfunction and transmit incorrect signals to the brain or it may be due to the malfunction of the olfactory neurons.
Unlike other nerve cells, which cannot regenerate, olfactory neurons die and are replaced throughout life, and scientists would love to learn how the smell cells accomplish what eludes the constituents of the spinal cord or neocortex.
The initial step in odor identification is interaction of an odorant molecule with olfactory (odorant) receptors (ORs) expressed at the surface of cilia of chemosensory olfactory neurons in the olfactory epithelium.
Katz and his colleagues combined biochemistry and physiology to discover a mouse social pheromone-purifying a single, vanishingly rare molecule (methylthio)methanethiol (MeSCHSH; MTMT) from mouse urine based on its ability to stimulate olfactory neurons.
CNGA2, previously called the olfactory α subunit and CNGA4, previously called the olfactory β subunit, are involved in transduction of odorant signals in olfactory neurons for which the subunit stoichiometry and arrangement are unknown.
Characteristics of these stages include: the role of olfactory plume and sniffing, the continuous renewal of Glomerulus receptors throughout the life cycle, and the relationship between the olfactory neuron and the glomerulus, and finally, the synthetic nature of glomerulus coding.
Bowman's glands (a.k.a. olfactory glands, glands of Bowman) are situated in the olfactory mucosa, beneath the olfactory epithelium, in the lamina propria, a connective tissue also containing fibroblasts, blood vessels, and bundles of fine axons from the olfactory neurons.
Slit1 and Slit2 mediate the repulsive activity of the septum and choroid plexus which orient the migration of undifferentiated cells of the subventricular zone (SVZ) on the rostral migratory stream (RMS) to the olfactory bulb, where they differentiate into olfactory neurons.
They are also known as olfactory Schwann cells because they ensheath the non-myelinated axons of olfactory neurones in a similar way to which Schwann cells ensheath non-myelinated peripheral neurons.