nucleotide cyclase

Consistent with these observations, both CyaB and ThTPase have been shown to require Mg 2+ions for their nucleotide cyclase and phosphatase activities [ 16 17 ] .

It has been named CHASE (Cyclases/Histidine kinases Associated Sensory Extracellular) because of its presence in diverse receptor-like proteins with histidine kinase and nucleotide cyclase domains.

HD domains typically possess phosphoesterase activity, and are fused to catalytic domains that possess nucleotide kinase, nucleotidyltransferase, nucleotide cyclase or diguanylate cyclase activity [ 19 29 ] .