normal phosphate

This thiophosphate acts the same as a normal phosphate group, although there is a slight bias against it by most polymerases.

(He 1998) Partitioning experiments have demonstrated that boranophosphates are more lipophilic than normal phosphates; (Shaw 2000) this could allow for increased cellular uptake and targeted delivery.

(Sood 1990) The boranophosphate resembles the normal phosphate in that the negative charge is retained; however, the polarity of the molecule changes because the negative charge is localized on the remaining non-bridging oxygen.