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The toxins can be typed with neutralization tests in mice.
Serologic studies have distinguished 66 human enterovirus serotypes on the basis of antibody neutralization tests.
The Plaque reduction neutralization test is used to quantify the titre of neutralising antibody for a virus.
Electron microscopy, PCR, complement fixation, antibody fluorescence, neutralization test and haemagglutination can be used to identify the virus in tissues or secretions.
This additional testing (e.g., the plaque-reduction neutralization test, PRNT) may require growth of the virus and may take a week or longer (plus shipping time) to conduct.
There are many alternative health care practitioners who perform a variety of provocation neutralization tests, but the vast majority of these tests have no validity and have never been proven to work scientifically.
The virus neutralization tests from all three laboratories indicate that the male patient, a 32-year-old television producer in Guangzhou, Guangdong Province, has recently been exposed to a SARS coronavirus (CoV).
Definitive diagnosis is typically made in a laboratory by employing some combination of blood tests, particularly immunologic, serologic and/or virologic techniques such as ELISA, complement fixation, polymerase chain reaction, neutralization test and hemagglutination-inhibition test.
Laboratory diagnosis of TOSV infection can be performed through the use of ELISA, immunofluorescence and/or neutralization tests, but reverse transcription, real-time polymerase chain reaction assays are preferred because they are less time-consuming and reduce the risk of contamination.